Pristimerin attenuates cell proliferation of uveal melanoma cells by inhibiting insulin‐like growth factor‐1 receptor and its downstream pathways

Uveal melanoma (UM) has a high mortality rate due to liver metastasis. The insulin‐like growth factor‐1 receptor (IGF‐1R) is highly expressed in UM and has been shown to be associated with hepatic metastases. Targeting IGF signalling may be considered as a promising approach to inhibit the process o...

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Detalles Bibliográficos
Autores principales: Xie, Xinshu, Xie, Saisai, Xie, Changying, Fang, Yuanying, Li, Zhifeng, Wang, Rikang, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815816/
https://www.ncbi.nlm.nih.gov/pubmed/31508890
http://dx.doi.org/10.1111/jcmm.14623

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