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PCSK9 inhibitor improves cardiac function and reduces infarct size in rats with ischaemia/reperfusion injury: Benefits beyond lipid‐lowering effects

During acute cardiac ischaemia/reperfusion (I/R), an increased plasma proprotein convertase subtilisin/kexin 9 (PCSK9) level instigates inflammatory and oxidative processes within ventricular myocytes, resulting in cardiac dysfunction. Therefore, PCSK9 inhibitor (PCSK9i) might exert cardioprotection...

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Detalles Bibliográficos
Autores principales:	Palee, Siripong, McSweeney, Christian M., Maneechote, Chayodom, Moisescu, Dalila M., Jaiwongkam, Thidarat, Kerdphoo, Sasiwan, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815840/ https://www.ncbi.nlm.nih.gov/pubmed/31557388 http://dx.doi.org/10.1111/jcmm.14586

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