Sigma‐1 receptor protects against ferroptosis in hepatocellular carcinoma cells

Sigma‐1 receptor (S1R) regulates reactive oxygen species (ROS) accumulation via nuclear factor erythroid 2‐related factor 2 (NRF2), which plays a vital role in ferroptosis. Sorafenib is a strong inducer of ferroptosis but not of apoptosis. However, the mechanism of sorafenib‐induced ferroptosis in h...

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Detalles Bibliográficos
Autores principales: Bai, Tao, Lei, Pengxu, Zhou, Hao, Liang, Ruopeng, Zhu, Rongtao, Wang, Weijie, Zhou, Lin, Sun, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815844/
https://www.ncbi.nlm.nih.gov/pubmed/31507082
http://dx.doi.org/10.1111/jcmm.14594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815844/
https://www.ncbi.nlm.nih.gov/pubmed/31507082
http://dx.doi.org/10.1111/jcmm.14594

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