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Sigma‐1 receptor protects against ferroptosis in hepatocellular carcinoma cells

Sigma‐1 receptor (S1R) regulates reactive oxygen species (ROS) accumulation via nuclear factor erythroid 2‐related factor 2 (NRF2), which plays a vital role in ferroptosis. Sorafenib is a strong inducer of ferroptosis but not of apoptosis. However, the mechanism of sorafenib‐induced ferroptosis in h...

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Detalles Bibliográficos
Autores principales:	Bai, Tao, Lei, Pengxu, Zhou, Hao, Liang, Ruopeng, Zhu, Rongtao, Wang, Weijie, Zhou, Lin, Sun, Yuling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815844/ https://www.ncbi.nlm.nih.gov/pubmed/31507082 http://dx.doi.org/10.1111/jcmm.14594

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