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Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran

BACKGROUND: One of the severe complications of toxoplasmosis is the induction of abortion in sheep, goats, and human beings. The rate of abortions related to toxoplasmosis in sheep varies between 10% and 23% in the United States and European countries. In Iran, Toxoplasma infection were diagnosed in...

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Autores principales: SHAHBAZI, Gholamreza, HOGHOOGHI RAD, Nasser, MADANI, Rassoul, MATIN, Somaieh, MORTAZAVI, Pedjman, JANGJOU, Amir Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815854/
https://www.ncbi.nlm.nih.gov/pubmed/31673261
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author SHAHBAZI, Gholamreza
HOGHOOGHI RAD, Nasser
MADANI, Rassoul
MATIN, Somaieh
MORTAZAVI, Pedjman
JANGJOU, Amir Hossein
author_facet SHAHBAZI, Gholamreza
HOGHOOGHI RAD, Nasser
MADANI, Rassoul
MATIN, Somaieh
MORTAZAVI, Pedjman
JANGJOU, Amir Hossein
author_sort SHAHBAZI, Gholamreza
collection PubMed
description BACKGROUND: One of the severe complications of toxoplasmosis is the induction of abortion in sheep, goats, and human beings. The rate of abortions related to toxoplasmosis in sheep varies between 10% and 23% in the United States and European countries. In Iran, Toxoplasma infection were diagnosed in aborted ovine fetuses between 13.5% and 69% in the brain samples based on PCR. The purpose of this study was to investigate the prevalence of abortions related to T. gondii among the aborted fetuses of sheep in Ardabil area, North-West of Iran. METHODS: The brains of 75 aborted sheep fetuses in Ardebil area were investigated with nested PCR method using fragments of the GRA6 gene during lambing seasons in 2014–2015. Meanwhile, thoracic and abdominal fluids of aborted fetuses and 200 serum samples collected from the herds affected by abortion were examined for the existence of anti-T. gondii IgG. RESULTS: For 48 out of the 75 fetal brain samples (64%), the results of nested PCR test were found to be positive. Furthermore, antibodies against Toxoplasma was observed in 136 (68%) collected samples of sheep and 21 samples (28%) of fetal fluids. CONCLUSION: There is the significant role of T. gondii in the abortions of sheep in Ardabil area. Meanwhile, this condition can also be dangerous for human beings because of their consumption of sheep meat.
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spelling pubmed-68158542019-10-31 Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran SHAHBAZI, Gholamreza HOGHOOGHI RAD, Nasser MADANI, Rassoul MATIN, Somaieh MORTAZAVI, Pedjman JANGJOU, Amir Hossein Iran J Parasitol Original Article BACKGROUND: One of the severe complications of toxoplasmosis is the induction of abortion in sheep, goats, and human beings. The rate of abortions related to toxoplasmosis in sheep varies between 10% and 23% in the United States and European countries. In Iran, Toxoplasma infection were diagnosed in aborted ovine fetuses between 13.5% and 69% in the brain samples based on PCR. The purpose of this study was to investigate the prevalence of abortions related to T. gondii among the aborted fetuses of sheep in Ardabil area, North-West of Iran. METHODS: The brains of 75 aborted sheep fetuses in Ardebil area were investigated with nested PCR method using fragments of the GRA6 gene during lambing seasons in 2014–2015. Meanwhile, thoracic and abdominal fluids of aborted fetuses and 200 serum samples collected from the herds affected by abortion were examined for the existence of anti-T. gondii IgG. RESULTS: For 48 out of the 75 fetal brain samples (64%), the results of nested PCR test were found to be positive. Furthermore, antibodies against Toxoplasma was observed in 136 (68%) collected samples of sheep and 21 samples (28%) of fetal fluids. CONCLUSION: There is the significant role of T. gondii in the abortions of sheep in Ardabil area. Meanwhile, this condition can also be dangerous for human beings because of their consumption of sheep meat. Tehran University of Medical Sciences 2019 /pmc/articles/PMC6815854/ /pubmed/31673261 Text en Copyright© Iranian Society of Parasitology & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
SHAHBAZI, Gholamreza
HOGHOOGHI RAD, Nasser
MADANI, Rassoul
MATIN, Somaieh
MORTAZAVI, Pedjman
JANGJOU, Amir Hossein
Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title_full Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title_fullStr Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title_full_unstemmed Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title_short Toxoplasma gondii in Aborted Fetuses of Sheep in Ardebil Area, North-West of Iran
title_sort toxoplasma gondii in aborted fetuses of sheep in ardebil area, north-west of iran
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815854/
https://www.ncbi.nlm.nih.gov/pubmed/31673261
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