Perineuritis Successfully Treated with Early Aggressive Immunotherapy

Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuri...

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Autores principales: Nakamura, Takumi, Kawarabayashi, Takeshi, Seino, Yusuke, Hirohata, Mie, Wakabayashi, Koichi, Shoji, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815884/
https://www.ncbi.nlm.nih.gov/pubmed/31243211
http://dx.doi.org/10.2169/internalmedicine.2638-19
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author Nakamura, Takumi
Kawarabayashi, Takeshi
Seino, Yusuke
Hirohata, Mie
Wakabayashi, Koichi
Shoji, Mikio
author_facet Nakamura, Takumi
Kawarabayashi, Takeshi
Seino, Yusuke
Hirohata, Mie
Wakabayashi, Koichi
Shoji, Mikio
author_sort Nakamura, Takumi
collection PubMed
description Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms.
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spelling pubmed-68158842019-10-29 Perineuritis Successfully Treated with Early Aggressive Immunotherapy Nakamura, Takumi Kawarabayashi, Takeshi Seino, Yusuke Hirohata, Mie Wakabayashi, Koichi Shoji, Mikio Intern Med Case Report Perineuritis is a rare type of peripheral neuropathy defined by swelling and cellular infiltration in the perineurium. We herein report a 52-year-old man who presented with subacute onset pain from the back to the lower limbs, muscle weakness and hypoesthesia. A sural nerve biopsy revealed perineuritis, consisting of inflammatory cell infiltration and swelling of the perineurium. Oral prednisolone, plasma exchange and intravenous immunoglobulin treatment were all effective, leading to significant improvement of the symptoms. The Japanese Society of Internal Medicine 2019-06-27 2019-10-01 /pmc/articles/PMC6815884/ /pubmed/31243211 http://dx.doi.org/10.2169/internalmedicine.2638-19 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nakamura, Takumi
Kawarabayashi, Takeshi
Seino, Yusuke
Hirohata, Mie
Wakabayashi, Koichi
Shoji, Mikio
Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title_full Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title_fullStr Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title_full_unstemmed Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title_short Perineuritis Successfully Treated with Early Aggressive Immunotherapy
title_sort perineuritis successfully treated with early aggressive immunotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815884/
https://www.ncbi.nlm.nih.gov/pubmed/31243211
http://dx.doi.org/10.2169/internalmedicine.2638-19
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