Cargando…

Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report

Complex aortic atheroma is a high-risk factor for recurrent embolic stroke. An accurate identification of stroke etiology is clinically important; however, it can be challenging. A 91-year-old man with atrial fibrillation was diagnosed with cardioembolic stroke and treated with mechanical thrombecto...

Descripción completa

Detalles Bibliográficos
Autores principales: Usui, Genki, Hashimoto, Hirotsugu, Sugiura, Yoshiya, Nishi, Yuji, Kusakabe, Masashi, Horiuchi, Hajime, Okubo, Seiji, Morikawa, Teppei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815896/
https://www.ncbi.nlm.nih.gov/pubmed/31178514
http://dx.doi.org/10.2169/internalmedicine.2857-19
_version_ 1783463279720398848
author Usui, Genki
Hashimoto, Hirotsugu
Sugiura, Yoshiya
Nishi, Yuji
Kusakabe, Masashi
Horiuchi, Hajime
Okubo, Seiji
Morikawa, Teppei
author_facet Usui, Genki
Hashimoto, Hirotsugu
Sugiura, Yoshiya
Nishi, Yuji
Kusakabe, Masashi
Horiuchi, Hajime
Okubo, Seiji
Morikawa, Teppei
author_sort Usui, Genki
collection PubMed
description Complex aortic atheroma is a high-risk factor for recurrent embolic stroke. An accurate identification of stroke etiology is clinically important; however, it can be challenging. A 91-year-old man with atrial fibrillation was diagnosed with cardioembolic stroke and treated with mechanical thrombectomy. The removed thrombus microscopically contained foamy cells, suggesting an atheroembolism. An autopsy revealed an atherosclerotic lesion with ulceration, located in the aortic arch. At the lesion, the plaque had microscopically ruptured into the lumen. We therefore concluded that the aortic atherosclerotic lesion was the embolic source. Removed thrombi should be pathologically examined even if a cardioembolic stroke is clinically suspected.
format Online
Article
Text
id pubmed-6815896
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-68158962019-10-29 Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report Usui, Genki Hashimoto, Hirotsugu Sugiura, Yoshiya Nishi, Yuji Kusakabe, Masashi Horiuchi, Hajime Okubo, Seiji Morikawa, Teppei Intern Med Case Report Complex aortic atheroma is a high-risk factor for recurrent embolic stroke. An accurate identification of stroke etiology is clinically important; however, it can be challenging. A 91-year-old man with atrial fibrillation was diagnosed with cardioembolic stroke and treated with mechanical thrombectomy. The removed thrombus microscopically contained foamy cells, suggesting an atheroembolism. An autopsy revealed an atherosclerotic lesion with ulceration, located in the aortic arch. At the lesion, the plaque had microscopically ruptured into the lumen. We therefore concluded that the aortic atherosclerotic lesion was the embolic source. Removed thrombi should be pathologically examined even if a cardioembolic stroke is clinically suspected. The Japanese Society of Internal Medicine 2019-06-07 2019-10-01 /pmc/articles/PMC6815896/ /pubmed/31178514 http://dx.doi.org/10.2169/internalmedicine.2857-19 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Usui, Genki
Hashimoto, Hirotsugu
Sugiura, Yoshiya
Nishi, Yuji
Kusakabe, Masashi
Horiuchi, Hajime
Okubo, Seiji
Morikawa, Teppei
Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title_full Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title_fullStr Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title_full_unstemmed Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title_short Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
title_sort aortogenic embolic stroke diagnosed by a pathological examination of endovascularly removed thrombus: an autopsy report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815896/
https://www.ncbi.nlm.nih.gov/pubmed/31178514
http://dx.doi.org/10.2169/internalmedicine.2857-19
work_keys_str_mv AT usuigenki aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT hashimotohirotsugu aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT sugiurayoshiya aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT nishiyuji aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT kusakabemasashi aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT horiuchihajime aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT okuboseiji aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport
AT morikawateppei aortogenicembolicstrokediagnosedbyapathologicalexaminationofendovascularlyremovedthrombusanautopsyreport