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Effects of Sitagliptin on the Coronary Flow Reserve, Circulating Endothelial Progenitor Cells and Stromal Cell-derived Factor-1alpha

OBJECTIVE: Circulating endothelial progenitor cells (EPCs) are regulated by stromal cell-derived factor-1alpha (SDF-1α) and are reduced in type 2 diabetes mellitus (DM). SDF-1α is a substrate of dipeptidyl-peptidase-4 (DPP-4), so we investigated whether or not DPP-4-inhibitors modulate EPC levels in...

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Detalles Bibliográficos
Autores principales: Morishita, Tetsuji, Uzui, Hiroyasu, Ikeda, Hiroyuki, Amaya, Naoki, Kaseno, Kenichi, Ishida, Kentaro, Fukuoka, Yoshitomo, Tada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815900/
https://www.ncbi.nlm.nih.gov/pubmed/31243210
http://dx.doi.org/10.2169/internalmedicine.2616-19

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