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Endoscopic management of esophageal cancer
Esophageal cancer (EC) generally consists of squamous cell carcinoma (which arise from squamous epithelium) and adenocarcinoma (which arise from columnar epithelium). Due to the increased recognition of risk factors associated with EC and the development of screening programs, there has been an incr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815921/ https://www.ncbi.nlm.nih.gov/pubmed/31662822 http://dx.doi.org/10.4251/wjgo.v11.i10.830 |
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author | Ahmed, Osman Ajani, Jaffer A Lee, Jeffrey H |
author_facet | Ahmed, Osman Ajani, Jaffer A Lee, Jeffrey H |
author_sort | Ahmed, Osman |
collection | PubMed |
description | Esophageal cancer (EC) generally consists of squamous cell carcinoma (which arise from squamous epithelium) and adenocarcinoma (which arise from columnar epithelium). Due to the increased recognition of risk factors associated with EC and the development of screening programs, there has been an increase in the diagnosis of early EC. Early EC is amenable to curative therapy by endoscopy, which can be performed by either endoscopic resection or endoscopic ablation. Endoscopic resection consists of either endoscopic mucosal resection (preferred in cases of adenocarcinoma) or endoscopic submucosal dissection (preferred in cases of squamous cell carcinoma). Endoscopic ablation can be performed by either radiofrequency ablation, cryotherapy, argon plasma coagulation or photodynamic therapy, amongst others. Endoscopy can also assist in the management of complications post-esophageal surgery, such as anastomotic leaks and perforations. Finally, there is a growing role for endoscopy to manage end-of-life palliative symptoms, especially dysphagia. The growing use of esophageal stents, debulking therapy and dilation can assist in improving a patient’s quality of life. In this review, we examine the multiple roles of endoscopy in the management of patients with EC. |
format | Online Article Text |
id | pubmed-6815921 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-68159212019-10-29 Endoscopic management of esophageal cancer Ahmed, Osman Ajani, Jaffer A Lee, Jeffrey H World J Gastrointest Oncol Minireviews Esophageal cancer (EC) generally consists of squamous cell carcinoma (which arise from squamous epithelium) and adenocarcinoma (which arise from columnar epithelium). Due to the increased recognition of risk factors associated with EC and the development of screening programs, there has been an increase in the diagnosis of early EC. Early EC is amenable to curative therapy by endoscopy, which can be performed by either endoscopic resection or endoscopic ablation. Endoscopic resection consists of either endoscopic mucosal resection (preferred in cases of adenocarcinoma) or endoscopic submucosal dissection (preferred in cases of squamous cell carcinoma). Endoscopic ablation can be performed by either radiofrequency ablation, cryotherapy, argon plasma coagulation or photodynamic therapy, amongst others. Endoscopy can also assist in the management of complications post-esophageal surgery, such as anastomotic leaks and perforations. Finally, there is a growing role for endoscopy to manage end-of-life palliative symptoms, especially dysphagia. The growing use of esophageal stents, debulking therapy and dilation can assist in improving a patient’s quality of life. In this review, we examine the multiple roles of endoscopy in the management of patients with EC. Baishideng Publishing Group Inc 2019-10-15 2019-10-15 /pmc/articles/PMC6815921/ /pubmed/31662822 http://dx.doi.org/10.4251/wjgo.v11.i10.830 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Minireviews Ahmed, Osman Ajani, Jaffer A Lee, Jeffrey H Endoscopic management of esophageal cancer |
title | Endoscopic management of esophageal cancer |
title_full | Endoscopic management of esophageal cancer |
title_fullStr | Endoscopic management of esophageal cancer |
title_full_unstemmed | Endoscopic management of esophageal cancer |
title_short | Endoscopic management of esophageal cancer |
title_sort | endoscopic management of esophageal cancer |
topic | Minireviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6815921/ https://www.ncbi.nlm.nih.gov/pubmed/31662822 http://dx.doi.org/10.4251/wjgo.v11.i10.830 |
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