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Effects of VEGF blockade on the dynamics of the inflammatory landscape in glioblastoma-bearing mice

BACKGROUND: Targeting angiogenesis has been and continues to be an attractive therapeutic modality in glioblastoma (GBM) patients. However, GBM rapidly becomes refractory to anti-VEGF therapies. Myeloid cell infiltration is an important determinant of tumor progression. Given that VEGF is a modulato...

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Detalles Bibliográficos
Autores principales:	Soubéran, Aurélie, Brustlein, Sophie, Gouarné, Caroline, Chasson, Lionel, Tchoghandjian, Aurélie, Malissen, Marie, Rougon, Geneviève
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816183/ https://www.ncbi.nlm.nih.gov/pubmed/31660979 http://dx.doi.org/10.1186/s12974-019-1563-8

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