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Reduced expression of PD-L1 in autoimmune thyroiditis attenuate trophoblast invasion through ERK/MMP pathway

BACKGROUND: Autoimmune thyroiditis (AIT) with euthyroid is associated with miscarriage. But the exact mechanism remains unclear. Studies have shown that the programmed cell death-1 (PD-1)/programmed cell death -ligand 1 (PD-L1) pathway is essential for normal pregnancy. However, the expression of PD...

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Detalles Bibliográficos
Autores principales:	Chen, Mengya, Gilbert, Nduwimana, Liu, Haixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816196/ https://www.ncbi.nlm.nih.gov/pubmed/31656199 http://dx.doi.org/10.1186/s12958-019-0536-1

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