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Characterization of cxorf21 Provides Molecular Insight Into Female-Bias Immune Response in SLE Pathogenesis

Background: Ninety percent of systemic lupus erythematosus (SLE) patients are women. X chromosome-dosage increases susceptibility to SLE and primary Sjögren's syndrome (pSS). Chromosome X open reading frame 21 (CXorf21) escapes X-inactivation and is an SLE risk gene of previously unknown functi...

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Detalles Bibliográficos
Autores principales:	Harris, Valerie M., Koelsch, Kristi A., Kurien, Biji T., Harley, Isaac T. W., Wren, Jonathan D., Harley, John B., Scofield, R. Hal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816314/ https://www.ncbi.nlm.nih.gov/pubmed/31695690 http://dx.doi.org/10.3389/fimmu.2019.02160

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