Native peptide mapping – A simple method to routinely monitor higher order structure changes and relation to functional activity

In the biopharmaceutical environment, controlling the Critical Quality Attributes (CQA) of a product is essential to prevent changes that affect its safety or efficacy. Physico-chemical techniques and bioassays are used to screen and monitor these CQAs. The higher order structure (HOS) is a CQA that...

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Detalles Bibliográficos
Autores principales: Degueldre, Michel, Wielant, Annemie, Girot, Eglantine, Burkitt, Will, O’Hara, John, Debauve, Gaël, Gervais, Annick, Jone, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816347/
https://www.ncbi.nlm.nih.gov/pubmed/31223055
http://dx.doi.org/10.1080/19420862.2019.1634460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816347/
https://www.ncbi.nlm.nih.gov/pubmed/31223055
http://dx.doi.org/10.1080/19420862.2019.1634460

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