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Compartmentalized DNA repair: Rif1 S-acylation links DNA double-strand break repair to the nuclear membrane

DNA double-strand breaks (DSBs) disrupt the structural integrity of chromosomes. Proper DSB repair pathway choice is critical to avoid the type of gross chromosomal rearrangements that characterize cancer cells. Recent findings reveal S-fatty acylation and membrane anchorage of Rap1-interacting fact...

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Detalles Bibliográficos
Autores principales:	Fontana, Gabriele A., Rass, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Author’s Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816362/ https://www.ncbi.nlm.nih.gov/pubmed/31692850 http://dx.doi.org/10.1080/23723556.2019.1648025

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