p16: cycling off the beaten path

p16(INK4A) (hereafter called p16) is a faithful cellular ally in the fight against tumorigenesis. Although its canonical pathway through retinoblastoma (RB) is well delineated, RB-independent functions for p16 are beginning to emerge. Here we summarize non-canonical roles of p16, including our recen...

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Detalles Bibliográficos
Autores principales: Buj, Raquel, Aird, Katherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Author's Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816386/
https://www.ncbi.nlm.nih.gov/pubmed/31692916
http://dx.doi.org/10.1080/23723556.2019.1677140
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author Buj, Raquel
Aird, Katherine M.
author_facet Buj, Raquel
Aird, Katherine M.
author_sort Buj, Raquel
collection PubMed
description p16(INK4A) (hereafter called p16) is a faithful cellular ally in the fight against tumorigenesis. Although its canonical pathway through retinoblastoma (RB) is well delineated, RB-independent functions for p16 are beginning to emerge. Here we summarize non-canonical roles of p16, including our recent finding on its role in nucleotide metabolism.
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spelling pubmed-68163862020-09-28 p16: cycling off the beaten path Buj, Raquel Aird, Katherine M. Mol Cell Oncol Author's Views p16(INK4A) (hereafter called p16) is a faithful cellular ally in the fight against tumorigenesis. Although its canonical pathway through retinoblastoma (RB) is well delineated, RB-independent functions for p16 are beginning to emerge. Here we summarize non-canonical roles of p16, including our recent finding on its role in nucleotide metabolism. Taylor & Francis 2019-10-15 /pmc/articles/PMC6816386/ /pubmed/31692916 http://dx.doi.org/10.1080/23723556.2019.1677140 Text en © 2019 The Author(s). Published by Taylor & Francis. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Author's Views
Buj, Raquel
Aird, Katherine M.
p16: cycling off the beaten path
title p16: cycling off the beaten path
title_full p16: cycling off the beaten path
title_fullStr p16: cycling off the beaten path
title_full_unstemmed p16: cycling off the beaten path
title_short p16: cycling off the beaten path
title_sort p16: cycling off the beaten path
topic Author's Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816386/
https://www.ncbi.nlm.nih.gov/pubmed/31692916
http://dx.doi.org/10.1080/23723556.2019.1677140
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