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A major interspecies difference in the ionic selectivity of megakaryocyte Ca(2+)-activated channels sensitive to the TMEM16F inhibitor CaCCinh-A01
TMEM16F is a surface membrane protein critical for platelet procoagulant activity, which exhibits both phospholipid scramblase and ion channel activities following sustained elevation of cytosolic Ca(2+). The extent to which the ionic permeability of TMEM16F is important for platelet scramblase resp...
Autores principales: | Taylor, Kirk A., Mahaut-Smith, Martyn P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6816474/ https://www.ncbi.nlm.nih.gov/pubmed/31008669 http://dx.doi.org/10.1080/09537104.2019.1595560 |
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