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Enzymatic control of cycloadduct conformation ensures reversible 1,3 dipolar cycloaddition in a prFMN dependent decarboxylase
The UbiD enzyme plays an important role in bacterial ubiquinone (coenzyme Q) biosynthesis. It belongs to a family of reversible decarboxylases that interconvert propenoic or aromatic acids with the corresponding alkenes or aromatic compounds using a prenylated flavin (prFMN) cofactor. This cofactor...
Autores principales: | Bailey, Samuel S., Payne, Karl A. P., Saaret, Annica, Marshall, Stephen A., Gostimskaya, Irina, Kosov, Iaroslav, Fisher, Karl, Hay, Sam, Leys, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817360/ https://www.ncbi.nlm.nih.gov/pubmed/31527849 http://dx.doi.org/10.1038/s41557-019-0324-8 |
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