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Hyperpolarized in vivo pH imaging reveals grade-dependent acidification in prostate cancer
There is an unmet clinical need for new and robust imaging biomarkers to distinguish indolent from aggressive prostate cancer. Hallmarks of aggressive tumors such as a decrease in extracellular pH (pH(e)) can potentially be used to identify aggressive phenotypes. In this study, we employ an optimize...
Autores principales: | Korenchan, David E., Bok, Robert, Sriram, Renuka, Liu, Kristina, Santos, Romelyn Delos, Qin, Hecong, Lobach, Iryna, Korn, Natalie, Wilson, David M., Kurhanewicz, John, Flavell, Robert R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817439/ https://www.ncbi.nlm.nih.gov/pubmed/31692908 http://dx.doi.org/10.18632/oncotarget.27225 |
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