Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells

Therapeutic effects of FLT3 inhibitors have been reported in acute myeloid leukemia (AML) with constitutively activating FLT3 mutations, including internal tandem duplication (ITD) and point mutation, which are found in approximately one-third of AML patients. One of the critical issues of treatment...

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Detalles Bibliográficos
Autores principales: Kawase, Tatsuya, Nakazawa, Taisuke, Eguchi, Tomohiro, Tsuzuki, Hirofumi, Ueno, Yoko, Amano, Yasushi, Suzuki, Tomoyuki, Mori, Masamichi, Yoshida, Taku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817455/
https://www.ncbi.nlm.nih.gov/pubmed/31692922
http://dx.doi.org/10.18632/oncotarget.27222

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