Cargando…

Pterostilbene, An Active Constituent of Blueberries, Suppresses Proliferation Potential of Human Cholangiocarcinoma via Enhancing the Autophagic Flux

Background: Human cholangiocarcinoma (CCA) is a highly lethal cancer that occurs in the biliary tract. It is characterized by early invasion, poor outcomes, and resistance to current chemotherapies. To date, an effective therapeutic strategy for this devastating and deadly disease is lacking. Pteros...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Dong, Guo, Haoran, Yang, Huahong, Wang, Dongyin, Gao, Pujun, Wei, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817474/ https://www.ncbi.nlm.nih.gov/pubmed/31695612 http://dx.doi.org/10.3389/fphar.2019.01238

Ejemplares similares

Pterostilbene, an active constituent of blueberries, enhances innate immune activation and restricts enterovirus D68 infection
por: Yang, Qingran, et al.
Publicado: (2023)

Iron Promotes Dihydroartemisinin Cytotoxicity via ROS Production and Blockade of Autophagic Flux via Lysosomal Damage in Osteosarcoma
por: Shen, Ying, et al.
Publicado: (2020)

Neuroprotective and Anti-Inflammatory Effect of Pterostilbene Against Cerebral Ischemia/Reperfusion Injury via Suppression of COX-2
por: Yan, Wenjun, et al.
Publicado: (2021)

Salinomycin inhibits cholangiocarcinoma growth by inhibition of autophagic flux
por: Klose, Johannes, et al.
Publicado: (2017)

Acylated Ghrelin is Protective Against 6-OHDA-induced Neurotoxicity by Regulating Autophagic Flux
por: He, Xin, et al.
Publicado: (2021)

Gintonin stimulates autophagic flux in primary cortical astrocytes
por: Rahman, Md. Ataur, et al.
Publicado: (2020)

Ubc9 Attenuates Myocardial Ischemic Injury Through Accelerating Autophagic Flux
por: Xiao, Qing, et al.
Publicado: (2020)

Modified 5-aminolevulinic acid photodynamic therapy suppresses cutaneous squamous cell carcinoma through blocking Akt/mTOR-mediated autophagic flux
por: Zeng, Qingyu, et al.
Publicado: (2023)

BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux
por: Shen, Shuangjun, et al.
Publicado: (2020)

Berberine Ameliorates High Glucose-Induced Cardiomyocyte Injury via AMPK Signaling Activation to Stimulate Mitochondrial Biogenesis and Restore Autophagic Flux
por: Hang, Weijian, et al.
Publicado: (2018)

Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway
por: Li, Jin, et al.
Publicado: (2016)

Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development
por: Zhou, Haikang, et al.
Publicado: (2021)

β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells
por: Jalal, Sajid, et al.
Publicado: (2022)

Thioredoxin-1 Activation by Pterostilbene Protects Against Doxorubicin-Induced Hepatotoxicity via Inhibiting the NLRP3 Inflammasome
por: Tan, Shiqing, et al.
Publicado: (2022)

9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2021)

Surgical procedures suppress autophagic flux in the kidney
por: Brown, Carolyn N., et al.
Publicado: (2021)

Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages
por: Ma, Chuanrui, et al.
Publicado: (2021)

Corrigendum: 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice
por: Wang, Yan-Mei, et al.
Publicado: (2022)

Fangchinoline inhibits the PEDV replication in intestinal epithelial cells via autophagic flux suppression
por: Zhang, Weixiao, et al.
Publicado: (2023)

BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells
por: Lee, Chi-Ming, et al.
Publicado: (2013)

Andrographolide Prevents EV-D68 Replication by Inhibiting the Acidification of Virus-Containing Endocytic Vesicles
por: Wang, Dongyin, et al.
Publicado: (2018)

Gap Junction Intercellular Communication Negatively Regulates Cadmium-Induced Autophagy and Inhibition of Autophagic Flux in Buffalo Rat Liver 3A Cells
por: Zou, Hui, et al.
Publicado: (2020)

Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer CAR cells via AKT signaling
por: Chang, Hui-Ping, et al.
Publicado: (2018)

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway
por: Li, Yali, et al.
Publicado: (2022)

β-Asarone Attenuates Aβ-Induced Neuronal Damage in PC12 Cells Overexpressing APPswe by Restoring Autophagic Flux
por: Li, Zhenwan, et al.
Publicado: (2021)

Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases
por: Suárez-Rivero, Juan M., et al.
Publicado: (2022)

Corilagin Alleviates Nonalcoholic Fatty Liver Disease in High-Fat Diet-Induced C57BL/6 Mice by Ameliorating Oxidative Stress and Restoring Autophagic Flux
por: Zhang, Rong, et al.
Publicado: (2020)

N-Desmethyldauricine Induces Autophagic Cell Death in Apoptosis-Defective Cells via Ca(2+) Mobilization
por: Law, Betty Y. K., et al.
Publicado: (2017)

Natural compound oblongifolin C inhibits autophagic flux, and induces apoptosis and mitochondrial dysfunction in human cholangiocarcinoma QBC939 cells
por: Zhang, Aiqing, et al.
Publicado: (2016)

Tumor microenvironment mediated by suppression of autophagic flux drives liver malignancy
por: Chen, Kuang-Den, et al.
Publicado: (2018)

TRIM39 deficiency inhibits tumor progression and autophagic flux in colorectal cancer via suppressing the activity of Rab7
por: Hu, Jia, et al.
Publicado: (2021)

Topical Ascorbic Acid Ameliorates Oxidative Stress-Induced Corneal Endothelial Damage via Suppression of Apoptosis and Autophagic Flux Blockage
por: Hsueh, Yi-Jen, et al.
Publicado: (2020)

SIRT1 Is Involved in the Neuroprotection of Pterostilbene Against Amyloid β 25–35-Induced Cognitive Deficits in Mice
por: Zhu, Lin, et al.
Publicado: (2022)

Hypoglycemic activity and constituents analysis of blueberry (Vaccinium corymbosum) fruit extracts
por: Huang, Weifeng, et al.
Publicado: (2018)

ox-LDL induces autophagy-mediated apoptosis by suppressing secretagogin-regulated autophagic flux in pancreatic β-cells: SCGN regulates autophagic flux in β-cells
por: Lv, Ying, et al.
Publicado: (2022)

Five Constituents Contributed to the Psoraleae Fructus-Induced Hepatotoxicity via Mitochondrial Dysfunction and Apoptosis
por: Guo, Zhaojuan, et al.
Publicado: (2021)

AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD (+) elevation
por: Han, Xiaojuan, et al.
Publicado: (2016)

Metformin suppresses vascular smooth muscle cell senescence by promoting autophagic flux
por: Tai, Shi, et al.
Publicado: (2021)

Pterostilbene Activates the Nrf2-Dependent Antioxidant Response to Ameliorate Arsenic-Induced Intracellular Damage and Apoptosis in Human Keratinocytes
por: Zhou, Junfeng, et al.
Publicado: (2019)

Protective Effects of Pterostilbene on Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting NF-κB and Activating Nrf2/HO-1 Signaling Pathways
por: Zhang, Yong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_29a3lpkd8pa33n2vtkbvpihon4