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Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report
Granulocytic sarcoma (chloroma) is a rare malignant solid tumor representing an extramedullary manifestation of acute myeloid leukemia (AML). Rarely, a chloroma can develop as the sole manifestation and its appearance may precede the systemic manifestations of acute myelocytic leukemia by months to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817491/ https://www.ncbi.nlm.nih.gov/pubmed/31695517 http://dx.doi.org/10.2147/IMCRJ.S206596 |
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author | Almalki, Ashwaq Mohammed J Alotaibi, Faisal Ali Jabr, Hatim Fawzi Mastan, Abdul Rehman |
author_facet | Almalki, Ashwaq Mohammed J Alotaibi, Faisal Ali Jabr, Hatim Fawzi Mastan, Abdul Rehman |
author_sort | Almalki, Ashwaq Mohammed J |
collection | PubMed |
description | Granulocytic sarcoma (chloroma) is a rare malignant solid tumor representing an extramedullary manifestation of acute myeloid leukemia (AML). Rarely, a chloroma can develop as the sole manifestation and its appearance may precede the systemic manifestations of acute myelocytic leukemia by months to years. We report a rare case of unilateral orbital mass presenting with progressive proptosis involving left globe in an otherwise healthy child, and give a brief overview of the literature about this unusual presentation. Leukemic infiltration should be considered in the differential diagnosis of orbital masses and proptosis even in the absence of systemic manifestations of AML. Early detection and management are crucial to preserve vision and prevent complications. |
format | Online Article Text |
id | pubmed-6817491 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-68174912019-11-06 Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report Almalki, Ashwaq Mohammed J Alotaibi, Faisal Ali Jabr, Hatim Fawzi Mastan, Abdul Rehman Int Med Case Rep J Case Report Granulocytic sarcoma (chloroma) is a rare malignant solid tumor representing an extramedullary manifestation of acute myeloid leukemia (AML). Rarely, a chloroma can develop as the sole manifestation and its appearance may precede the systemic manifestations of acute myelocytic leukemia by months to years. We report a rare case of unilateral orbital mass presenting with progressive proptosis involving left globe in an otherwise healthy child, and give a brief overview of the literature about this unusual presentation. Leukemic infiltration should be considered in the differential diagnosis of orbital masses and proptosis even in the absence of systemic manifestations of AML. Early detection and management are crucial to preserve vision and prevent complications. Dove 2019-10-24 /pmc/articles/PMC6817491/ /pubmed/31695517 http://dx.doi.org/10.2147/IMCRJ.S206596 Text en © 2019 Almalki et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Almalki, Ashwaq Mohammed J Alotaibi, Faisal Ali Jabr, Hatim Fawzi Mastan, Abdul Rehman Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title | Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title_full | Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title_fullStr | Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title_full_unstemmed | Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title_short | Unilateral Proptosis As An Initial Sign Of Acute Myeloid Leukemia In A Child: A Case Report |
title_sort | unilateral proptosis as an initial sign of acute myeloid leukemia in a child: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817491/ https://www.ncbi.nlm.nih.gov/pubmed/31695517 http://dx.doi.org/10.2147/IMCRJ.S206596 |
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