Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation

Neutrophils respond to various stimuli by decondensing and releasing nuclear chromatin characterized by citrullinated histones as neutrophil extracellular traps (NETs). This achieves pathogen immobilization or initiation of thrombosis, yet the molecular mechanisms of NET formation remain elusive. Pe...

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Detalles Bibliográficos
Autores principales: Gößwein, Stefanie, Lindemann, Aylin, Mahajan, Aparna, Maueröder, Christian, Martini, Eva, Patankar, Jay, Schett, Georg, Becker, Christoph, Wirtz, Stefan, Naumann-Bartsch, Nora, Bianchi, Marco E., Greer, Peter A., Lochnit, Günter, Herrmann, Martin, Neurath, Markus F., Leppkes, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817590/
https://www.ncbi.nlm.nih.gov/pubmed/31695698
http://dx.doi.org/10.3389/fimmu.2019.02481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817590/
https://www.ncbi.nlm.nih.gov/pubmed/31695698
http://dx.doi.org/10.3389/fimmu.2019.02481

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