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Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation
Neutrophils respond to various stimuli by decondensing and releasing nuclear chromatin characterized by citrullinated histones as neutrophil extracellular traps (NETs). This achieves pathogen immobilization or initiation of thrombosis, yet the molecular mechanisms of NET formation remain elusive. Pe...
Autores principales: | Gößwein, Stefanie, Lindemann, Aylin, Mahajan, Aparna, Maueröder, Christian, Martini, Eva, Patankar, Jay, Schett, Georg, Becker, Christoph, Wirtz, Stefan, Naumann-Bartsch, Nora, Bianchi, Marco E., Greer, Peter A., Lochnit, Günter, Herrmann, Martin, Neurath, Markus F., Leppkes, Moritz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817590/ https://www.ncbi.nlm.nih.gov/pubmed/31695698 http://dx.doi.org/10.3389/fimmu.2019.02481 |
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