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Adolescent rat social play: Amygdalar proteomic and transcriptomic data

This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural animals. Social play was performed on male Sprague Dawley rats on postnatal day 38 and protein and gene expression in the amygdala was determined fo...

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Autores principales: Alugubelly, Navatha, Mohammed, Afzaal N., Edelmann, Mariola J., Nanduri, Bindu, Sayed, Mohammed, Park, Juw Won, Carr, Russell L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817652/
https://www.ncbi.nlm.nih.gov/pubmed/31673590
http://dx.doi.org/10.1016/j.dib.2019.104589
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author Alugubelly, Navatha
Mohammed, Afzaal N.
Edelmann, Mariola J.
Nanduri, Bindu
Sayed, Mohammed
Park, Juw Won
Carr, Russell L.
author_facet Alugubelly, Navatha
Mohammed, Afzaal N.
Edelmann, Mariola J.
Nanduri, Bindu
Sayed, Mohammed
Park, Juw Won
Carr, Russell L.
author_sort Alugubelly, Navatha
collection PubMed
description This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural animals. Social play was performed on male Sprague Dawley rats on postnatal day 38 and protein and gene expression in the amygdala was determined following behavioural testing. The protein expression was measured by analysing trypsin digested protein samples using a LTQ Orbitrap Velos mass spectrometer equipped with an Advion nanomate ESI source. The obtained tandem mass spectra were extracted by Thermo Proteome Discoverer 1.3 and the data were displayed with Scaffold v 4.5.1. The transcriptomic data were generated by llumina HiSeq 4000 system. Cuffdiff (v2.2.1) program was used to calculate RNA-seq based gene expression levels. For further interpretation of data presented in this article, please see the research article ‘Proteomic and Transcriptional Profiling of Rat Amygdala Following Social Play’ (Alugubelly et al. 2019).
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spelling pubmed-68176522019-10-31 Adolescent rat social play: Amygdalar proteomic and transcriptomic data Alugubelly, Navatha Mohammed, Afzaal N. Edelmann, Mariola J. Nanduri, Bindu Sayed, Mohammed Park, Juw Won Carr, Russell L. Data Brief Neuroscience This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural animals. Social play was performed on male Sprague Dawley rats on postnatal day 38 and protein and gene expression in the amygdala was determined following behavioural testing. The protein expression was measured by analysing trypsin digested protein samples using a LTQ Orbitrap Velos mass spectrometer equipped with an Advion nanomate ESI source. The obtained tandem mass spectra were extracted by Thermo Proteome Discoverer 1.3 and the data were displayed with Scaffold v 4.5.1. The transcriptomic data were generated by llumina HiSeq 4000 system. Cuffdiff (v2.2.1) program was used to calculate RNA-seq based gene expression levels. For further interpretation of data presented in this article, please see the research article ‘Proteomic and Transcriptional Profiling of Rat Amygdala Following Social Play’ (Alugubelly et al. 2019). Elsevier 2019-09-30 /pmc/articles/PMC6817652/ /pubmed/31673590 http://dx.doi.org/10.1016/j.dib.2019.104589 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Neuroscience
Alugubelly, Navatha
Mohammed, Afzaal N.
Edelmann, Mariola J.
Nanduri, Bindu
Sayed, Mohammed
Park, Juw Won
Carr, Russell L.
Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title_full Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title_fullStr Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title_full_unstemmed Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title_short Adolescent rat social play: Amygdalar proteomic and transcriptomic data
title_sort adolescent rat social play: amygdalar proteomic and transcriptomic data
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817652/
https://www.ncbi.nlm.nih.gov/pubmed/31673590
http://dx.doi.org/10.1016/j.dib.2019.104589
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