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Circumscribed choroidal haemangioma: clinical and topographical features

AIMS: To characterise the clinical and topographical features of circumscribed choroidal haemangioma (CCH) and to visualise the patterns of tumour extent in the ocular fundus. METHODS: Data on the size, shape and location of 113 CCH were converted into a database of two-dimensional retinal charts by...

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Autores principales: Krohn, Jørgen, Rishi, Pukhraj, Frøystein, Torbjørn, Singh, Arun D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817701/
https://www.ncbi.nlm.nih.gov/pubmed/30602446
http://dx.doi.org/10.1136/bjophthalmol-2018-313388
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author Krohn, Jørgen
Rishi, Pukhraj
Frøystein, Torbjørn
Singh, Arun D
author_facet Krohn, Jørgen
Rishi, Pukhraj
Frøystein, Torbjørn
Singh, Arun D
author_sort Krohn, Jørgen
collection PubMed
description AIMS: To characterise the clinical and topographical features of circumscribed choroidal haemangioma (CCH) and to visualise the patterns of tumour extent in the ocular fundus. METHODS: Data on the size, shape and location of 113 CCH were converted into a database of two-dimensional retinal charts by means of computer drawing software. The extent of the tumours was visualised by merging the charts and displaying the number of overlapping tumours on colour-coded maps. RESULTS: The mean largest tumour diameter was 7.2 mm (range, 2.5–11.0 mm), mean tumour height was 2.4 mm (range, 0.7–4.6 mm) and mean diameter/height ratio was 3.2 (range, 2.1–6.0). The mean distance from the posterior tumour margin to the foveola and optic disc margin was 1.7 mm (range, 0–15 mm) and 2.4 mm (range, 0–11 mm), respectively. The hemispheric location of the tumour centroid was temporal in 75 eyes (66%) and nasal in 38 (34%) (p=0.0005) and the distribution between the superior and inferior hemispheres was 68 (60%) and 45 (40%), respectively (p=0.03). The presence of subretinal fluid (SRF) was significantly associated with young age at diagnosis (p=0.0002), low tumour diameter/height ratio (p=0.0004), nasal hemisphere location (p=0.006) and close proximity to the optic disc (p=0.004). CONCLUSIONS: The superotemporal quadrant close to the macula is the most frequent location of CCH. The tumours are generally characterised by a diameter/height ratio of >2. Tumours in young patients, with marked elevation, in nasal hemisphere and in proximity to the optic disc are associated with SRF exudation.
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spelling pubmed-68177012019-11-12 Circumscribed choroidal haemangioma: clinical and topographical features Krohn, Jørgen Rishi, Pukhraj Frøystein, Torbjørn Singh, Arun D Br J Ophthalmol Clinical Science AIMS: To characterise the clinical and topographical features of circumscribed choroidal haemangioma (CCH) and to visualise the patterns of tumour extent in the ocular fundus. METHODS: Data on the size, shape and location of 113 CCH were converted into a database of two-dimensional retinal charts by means of computer drawing software. The extent of the tumours was visualised by merging the charts and displaying the number of overlapping tumours on colour-coded maps. RESULTS: The mean largest tumour diameter was 7.2 mm (range, 2.5–11.0 mm), mean tumour height was 2.4 mm (range, 0.7–4.6 mm) and mean diameter/height ratio was 3.2 (range, 2.1–6.0). The mean distance from the posterior tumour margin to the foveola and optic disc margin was 1.7 mm (range, 0–15 mm) and 2.4 mm (range, 0–11 mm), respectively. The hemispheric location of the tumour centroid was temporal in 75 eyes (66%) and nasal in 38 (34%) (p=0.0005) and the distribution between the superior and inferior hemispheres was 68 (60%) and 45 (40%), respectively (p=0.03). The presence of subretinal fluid (SRF) was significantly associated with young age at diagnosis (p=0.0002), low tumour diameter/height ratio (p=0.0004), nasal hemisphere location (p=0.006) and close proximity to the optic disc (p=0.004). CONCLUSIONS: The superotemporal quadrant close to the macula is the most frequent location of CCH. The tumours are generally characterised by a diameter/height ratio of >2. Tumours in young patients, with marked elevation, in nasal hemisphere and in proximity to the optic disc are associated with SRF exudation. BMJ Publishing Group 2019-10 2019-01-02 /pmc/articles/PMC6817701/ /pubmed/30602446 http://dx.doi.org/10.1136/bjophthalmol-2018-313388 Text en © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Clinical Science
Krohn, Jørgen
Rishi, Pukhraj
Frøystein, Torbjørn
Singh, Arun D
Circumscribed choroidal haemangioma: clinical and topographical features
title Circumscribed choroidal haemangioma: clinical and topographical features
title_full Circumscribed choroidal haemangioma: clinical and topographical features
title_fullStr Circumscribed choroidal haemangioma: clinical and topographical features
title_full_unstemmed Circumscribed choroidal haemangioma: clinical and topographical features
title_short Circumscribed choroidal haemangioma: clinical and topographical features
title_sort circumscribed choroidal haemangioma: clinical and topographical features
topic Clinical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817701/
https://www.ncbi.nlm.nih.gov/pubmed/30602446
http://dx.doi.org/10.1136/bjophthalmol-2018-313388
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