Gremlin-1: An endogenous BMP antagonist induces epithelial-mesenchymal transition and interferes with redifferentiation in fetal RPE cells with repeated wounds

PURPOSE: To investigate the role of Gremlin-1, which is an endogenous antagonist of the bone morphogenetic protein (BMP) signaling pathway, in inducing epithelium-mesenchymal transition (EMT) in fetal RPE cells after repeated wounds. METHODS: Subconfluent repetitive passages in fetal RPE cells were...

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Detalles Bibliográficos
Autores principales: Li, Duo, Yuan, Dongqing, Shen, Han, Mao, Xiying, Yuan, Songtao, Liu, Qinghuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817737/
https://www.ncbi.nlm.nih.gov/pubmed/31700227

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