PR55α regulatory subunit of PP2A inhibits the MOB1/LATS cascade and activates YAP in pancreatic cancer cells

PP2A holoenzyme complexes are responsible for the majority of Ser/Thr phosphatase activities in human cells. Each PP2A consists of a catalytic subunit (C), a scaffold subunit (A), and a regulatory subunit (B). While the A and C subunits each exists only in two highly conserved isoforms, a large numb...

Descripción completa

Detalles Bibliográficos
Autores principales: Hein, Ashley L., Brandquist, Nichole D., Ouellette, Caroline Y., Seshacharyulu, Parthasarathy, Enke, Charles A., Ouellette, Michel M., Batra, Surinder K., Yan, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817822/
https://www.ncbi.nlm.nih.gov/pubmed/31659153
http://dx.doi.org/10.1038/s41389-019-0172-9

Ejemplares similares

Ejemplares similares