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Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells
Intercellular communication within the bone marrow niche significantly promotes leukemogenesis and provides protection of leukemic cells from therapy. Secreted factors, intercellular transfer of mitochondria and the receptor–ligand interactions have been shown as mediators of this protection. Here w...
Autores principales: | Kolba, Marta D., Dudka, Wioleta, Zaręba-Kozioł, Monika, Kominek, Agata, Ronchi, Paolo, Turos, Laura, Chroscicki, Piotr, Wlodarczyk, Jakub, Schwab, Yannick, Klejman, Agata, Cysewski, Dominik, Srpan, Katja, Davis, Daniel M., Piwocka, Katarzyna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817823/ https://www.ncbi.nlm.nih.gov/pubmed/31659149 http://dx.doi.org/10.1038/s41419-019-2045-8 |
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