Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia

The delivery of biologic cargoes to airway epithelial cells is challenging due to the formidable barriers imposed by its specialized and differentiated cells. Among cargoes, recombinant proteins offer therapeutic promise but the lack of effective delivery methods limits their development. Here, we a...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Sateesh, Wohlford-Lenane, Christine, Kandimalla, Suhas, Sartre, Gilles, Meyerholz, David K., Théberge, Vanessa, Hallée, Stéphanie, Duperré, Anne-Marie, Del’Guidice, Thomas, Lepetit-Stoffaes, Jean-Pascal, Barbeau, Xavier, Guay, David, McCray, Paul B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817825/
https://www.ncbi.nlm.nih.gov/pubmed/31659165
http://dx.doi.org/10.1038/s41467-019-12922-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817825/
https://www.ncbi.nlm.nih.gov/pubmed/31659165
http://dx.doi.org/10.1038/s41467-019-12922-y

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