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FOXC2 expression and epithelial–mesenchymal phenotypes are associated with castration resistance, metastasis and survival in prostate cancer

Epithelial–mesenchymal transition (EMT) is important for tumour cell invasion and metastasis and is a feature of aggressive carcinomas. EMT is characterised by reduced E‐cadherin and increased N‐cadherin expression (EN‐switch), and increased expression of the EMT‐regulating transcription factor Fork...

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Detalles Bibliográficos
Autores principales: Børretzen, Astrid, Gravdal, Karsten, Haukaas, Svein A, Beisland, Christian, Akslen, Lars A, Halvorsen, Ole J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817834/
https://www.ncbi.nlm.nih.gov/pubmed/31464093
http://dx.doi.org/10.1002/cjp2.142

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