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MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma

miR-18a has been reported to be upregulated in nasopharyngeal carcinoma (NPC) tissues by microarray assays. However, the roles and the underlying mechanisms of miR-18a in NPC remain poorly understood. Here we demonstrated by real-time RT-PCR that miR-18a expression is upregulated in NPC tissues, and...

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Detalles Bibliográficos
Autores principales: Mai, ShiJuan, Xiao, RuoWen, Shi, Lu, Zhou, XiaoMin, Yang, Te, Zhang, MeiYin, Weng, NuoQing, Zhao, XinGe, Wang, RuiQi, Liu, Ji, Sun, Rui, Qin, HaiDe, Wang, HuiYun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817863/
https://www.ncbi.nlm.nih.gov/pubmed/31659158
http://dx.doi.org/10.1038/s41419-019-2060-9

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