Cargando…

Is there a link between genetic defects in the complement cascade and Porphyromonas gingivalis in Alzheimer’s disease?

Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement cascade of innate immunity have been suggested to play a key role in Alzheimer’s disease (AD). These defective genes encode sub-component 1s (C1s), complement receptor 1, complement component 9, and clusterin, a flui...

Descripción completa

Detalles Bibliográficos
Autores principales: Olsen, Ingar, Singhrao, Sim K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818111/
https://www.ncbi.nlm.nih.gov/pubmed/31893014
http://dx.doi.org/10.1080/20002297.2019.1676486