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Is there a link between genetic defects in the complement cascade and Porphyromonas gingivalis in Alzheimer’s disease?
Defects, as determined by Genome-Wide Association Studies (GWAS), in the complement cascade of innate immunity have been suggested to play a key role in Alzheimer’s disease (AD). These defective genes encode sub-component 1s (C1s), complement receptor 1, complement component 9, and clusterin, a flui...
Autores principales: | Olsen, Ingar, Singhrao, Sim K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818111/ https://www.ncbi.nlm.nih.gov/pubmed/31893014 http://dx.doi.org/10.1080/20002297.2019.1676486 |
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