Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation

Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control pro...

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Detalles Bibliográficos
Autores principales: Le, Brian, Knoedler, Margaret, Roberge, Gray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Functional Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818137/
https://www.ncbi.nlm.nih.gov/pubmed/31681534
http://dx.doi.org/10.1016/j.eucr.2019.100914
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author Le, Brian
Knoedler, Margaret
Roberge, Gray
author_facet Le, Brian
Knoedler, Margaret
Roberge, Gray
author_sort Le, Brian
collection PubMed
description Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control prostatic bleeding. This patient's hematuria abated with endoscopic localized injection of tranexamic acid into the prostate. The effects were durable with no bleeding recurrence reported while maintaining therapeutic anticoagulation.
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spelling pubmed-68181372019-11-01 Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation Le, Brian Knoedler, Margaret Roberge, Gray Urol Case Rep Functional Medicine Tranexamic acid (TXA) has been used to manage menstrual bleeding and reduce bleeding during orthopedic procedures, but has not been widely used in urology. We present a patient with refractory gross hematuria with required therapeutic anticoagulation who failed multiple other measures to control prostatic bleeding. This patient's hematuria abated with endoscopic localized injection of tranexamic acid into the prostate. The effects were durable with no bleeding recurrence reported while maintaining therapeutic anticoagulation. Elsevier 2019-05-22 /pmc/articles/PMC6818137/ /pubmed/31681534 http://dx.doi.org/10.1016/j.eucr.2019.100914 Text en © 2019 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Functional Medicine
Le, Brian
Knoedler, Margaret
Roberge, Gray
Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_full Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_fullStr Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_full_unstemmed Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_short Intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
title_sort intraprostatic injection of tranexamic acid to control refractory bleeding while maintaining therapeutic anticoagulation
topic Functional Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818137/
https://www.ncbi.nlm.nih.gov/pubmed/31681534
http://dx.doi.org/10.1016/j.eucr.2019.100914
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AT robergegray intraprostaticinjectionoftranexamicacidtocontrolrefractorybleedingwhilemaintainingtherapeuticanticoagulation

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