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MicroRNA-425-5p Expression Affects BRAF/RAS/MAPK Pathways In Colorectal Cancers

Colorectal cancer (CRC) is a leading cause of cancer death worldwide and about 20% is metastatic at diagnosis and untreatable. The anti-EGFR therapy in metastatic patients is led by the presence of KRAS-mutations in tumor tissue. KRAS-wild-type CRC patients showed a positive response rate of about 7...

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Detalles Bibliográficos
Autores principales: Angius, Andrea, Pira, Giovanna, Scanu, Antonio Mario, Uva, Paolo, Sotgiu, Giovanni, Saderi, Laura, Manca, Alessandra, Serra, Caterina, Uleri, Elena, Piu, Claudia, Caocci, Maurizio, Ibba, Gabriele, Zinellu, Angelo, Cesaraccio, Maria Rosaria, Sanges, Francesca, Muroni, Maria Rosaria, Dolei, Antonina, Cossu-Rocca, Paolo, De Miglio, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818206/
https://www.ncbi.nlm.nih.gov/pubmed/31673240
http://dx.doi.org/10.7150/ijms.35269

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