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Characterization of Distinct T Cell Receptor Repertoires in Tumor and Distant Non-tumor Tissues from Lung Cancer Patients

T cells and T cell receptors (TCRs) play pivotal roles in adaptive immune responses against tumors. The development of next-generation sequencing technologies has enabled the analysis of the TCRβ repertoire usage. Given the scarce investigations on the TCR repertoire in lung cancer tissues, in this...

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Detalles Bibliográficos
Autores principales: Wang, Xiang, Zhang, Botao, Yang, Yikun, Zhu, Jiawei, Cheng, Shujun, Mao, Yousheng, Feng, Lin, Xiao, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818398/
https://www.ncbi.nlm.nih.gov/pubmed/31479759
http://dx.doi.org/10.1016/j.gpb.2018.10.005