Tumour‐derived transforming growth factor‐β signalling contributes to fibrosis in patients with cancer cachexia

BACKGROUND: Cachexia is a paraneoplastic syndrome related with poor prognosis. The tumour micro‐environment contributes to systemic inflammation and increased oxidative stress as well as to fibrosis. The aim of the present study was to characterise the inflammatory circulating factors and tumour mic...

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Detalles Bibliográficos
Autores principales: Lima, Joanna D.C.C., Simoes, Estefania, de Castro, Gabriela, Morais, Mychel Raony P.T., de Matos‐Neto, Emidio M., Alves, Michele J., Pinto, Nelson I., Figueredo, Raquel G., Zorn, Telma M.T., Felipe‐Silva, Aloísio S., Tokeshi, Flavio, Otoch, José P., Alcantara, Paulo, Cabral, Fernanda J., Ferro, Emer S., Laviano, Alessandro, Seelaender, Marilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818454/
https://www.ncbi.nlm.nih.gov/pubmed/31273954
http://dx.doi.org/10.1002/jcsm.12441

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