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Inhibition of myostatin improves muscle atrophy in oculopharyngeal muscular dystrophy (OPMD)

BACKGROUND: Oculopharyngeal muscular dystrophy (OPMD) is a late‐onset muscle disease affecting one per 80 000 of the general population characterized by profound dysphagia and ptosis, and limb weakness at later stages. Affected muscles are characterized by increased fibrosis and atrophy. Myostatin i...

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Detalles Bibliográficos
Autores principales: Harish, Pradeep, Malerba, Alberto, Lu‐Nguyen, Ngoc, Forrest, Leysa, Cappellari, Ornella, Roth, Fanny, Trollet, Capucine, Popplewell, Linda, Dickson, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818462/
https://www.ncbi.nlm.nih.gov/pubmed/31066242
http://dx.doi.org/10.1002/jcsm.12438

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