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The systemic activin response to pancreatic cancer: implications for effective cancer cachexia therapy

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a particularly lethal malignancy partly due to frequent, severe cachexia. Serum activin correlates with cachexia and mortality, while exogenous activin causes cachexia in mice. METHODS: Isoform‐specific activin expression and activities were que...

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Detalles Bibliográficos
Autores principales:	Zhong, Xiaoling, Pons, Marianne, Poirier, Christophe, Jiang, Yanlin, Liu, Jianguo, Sandusky, George E., Shahda, Safi, Nakeeb, Attila, Schmidt, C. Max, House, Michael G., Ceppa, Eugene P., Zyromski, Nicholas J., Liu, Yunlong, Jiang, Guanglong, Couch, Marion E., Koniaris, Leonidas G., Zimmers, Teresa A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818463/ https://www.ncbi.nlm.nih.gov/pubmed/31286691 http://dx.doi.org/10.1002/jcsm.12461

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