Cargando…

Metabolic effects of skeletal muscle-specific deletion of beta-arrestin-1 and -2 in mice

Type 2 diabetes (T2D) has become a major health problem worldwide. Skeletal muscle (SKM) is the key tissue for whole-body glucose disposal and utilization. New drugs aimed at improving insulin sensitivity of SKM would greatly expand available therapeutic options. β-arrestin-1 and -2 (Barr1 and Barr2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meister, Jaroslawna, Bone, Derek B. J., Godlewski, Grzegorz, Liu, Ziyi, Lee, Regina J., Vishnivetskiy, Sergey A., Gurevich, Vsevolod V., Springer, Danielle, Kunos, George, Wess, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818801/ https://www.ncbi.nlm.nih.gov/pubmed/31622341 http://dx.doi.org/10.1371/journal.pgen.1008424

Ejemplares similares

Structural Basis of Arrestin Selectivity for Active Phosphorylated G Protein-Coupled Receptors
por: Karnam, Preethi C., et al.
Publicado: (2021)

Functional Role of Arrestin-1 Residues Interacting with Unphosphorylated Rhodopsin Elements
por: Vishnivetskiy, Sergey A., et al.
Publicado: (2023)

The Role of Arrestin-1 Middle Loop in Rhodopsin Binding
por: Vishnivetskiy, Sergey A., et al.
Publicado: (2022)

Enhanced Mutant Compensates for Defects in Rhodopsin Phosphorylation in the Presence of Endogenous Arrestin-1
por: Samaranayake, Srimal, et al.
Publicado: (2018)

Molecular Defects of the Disease-Causing Human Arrestin-1 C147F Mutant
por: Vishnivetskiy, Sergey A., et al.
Publicado: (2018)

Uncovering missing pieces: duplication and deletion history of arrestins in deuterostomes
por: Indrischek, Henrike, et al.
Publicado: (2017)

Progressive Reduction of its Expression in Rods Reveals Two Pools of Arrestin-1 in the Outer Segment with Different Roles in Photoresponse Recovery
por: Cleghorn, Whitney M., et al.
Publicado: (2011)

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity
por: Barella, Luiz F., et al.
Publicado: (2021)

Structural basis of arrestin-3 activation and signaling
por: Chen, Qiuyan, et al.
Publicado: (2017)

β-arrestin-1 suppresses myogenic reprogramming of brown fat to maintain euglycemia
por: Pydi, Sai P., et al.
Publicado: (2020)

Arrestin-mediated signaling: Is there a controversy?
por: Gurevich, Vsevolod V, et al.
Publicado: (2018)

In vivo metabolic effects after acute activation of skeletal muscle G(s) signaling
por: Meister, Jaroslawna, et al.
Publicado: (2021)

Arrestins: ubiquitous regulators of cellular signaling pathways
por: Gurevich, Eugenia V, et al.
Publicado: (2006)

GPCR Signaling Regulation: The Role of GRKs and Arrestins
por: Gurevich, Vsevolod V., et al.
Publicado: (2019)

Do arrestin oligomers have specific functions?
por: Gurevich, Vsevolod V.
Publicado: (2023)

Solo vs. Chorus: Monomers and Oligomers of Arrestin Proteins
por: Gurevich, Vsevolod V., et al.
Publicado: (2022)

Receptor-Arrestin Interactions: The GPCR Perspective
por: Seyedabadi, Mohammad, et al.
Publicado: (2021)

Arrestins: structural disorder creates rich functionality
por: Gurevich, Vsevolod V., et al.
Publicado: (2018)

Arrestin Facilitates Rhodopsin Dephosphorylation in Vivo
por: Hsieh, Chia-Ling, et al.
Publicado: (2022)

Critical role of the finger loop in arrestin binding to the receptors
por: Zheng, Chen, et al.
Publicado: (2019)

Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB(1)R) Antagonist
por: Liu, Ziyi, et al.
Publicado: (2021)

Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells
por: Meister, Jaroslawna, et al.
Publicado: (2022)

The Two β-Arrestins Regulate Distinct Metabolic Processes: Studies with Novel Mutant Mouse Models
por: Wess, Jürgen
Publicado: (2022)

GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements
por: Zheng, Chen, et al.
Publicado: (2023)

GPCR binding and JNK3 activation by arrestin-3 have different structural requirements
por: Zheng, Chen, et al.
Publicado: (2023)

Exploring GPCR‐arrestin interfaces with genetically encoded crosslinkers
por: Böttke, Thore, et al.
Publicado: (2020)

Lack of beta-arrestin signaling in the absence of active G proteins
por: Grundmann, Manuel, et al.
Publicado: (2018)

Short Arrestin-3-Derived Peptides Activate JNK3 in Cells
por: Perry-Hauser, Nicole A., et al.
Publicado: (2022)

Arrestins regulate cell spreading and motility via focal adhesion dynamics
por: Cleghorn, Whitney M., et al.
Publicado: (2015)

Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo
por: Ahmed, Mohamed R., et al.
Publicado: (2023)

β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions
por: Zhu, Lu, et al.
Publicado: (2017)

Triphenylmethane Dye Activation of Beta-Arrestin
por: Barak, Larry S., et al.
Publicado: (2013)

Structural details of a Class B GPCR-arrestin complex revealed by genetically encoded crosslinkers in living cells
por: Aydin, Yasmin, et al.
Publicado: (2023)

The Effect of Arrestin Conformation on the Recruitment of c-Raf1, MEK1, and ERK1/2 Activation
por: Coffa, Sergio, et al.
Publicado: (2011)

Beta-Arrestins and Receptor Signaling in the Vascular Endothelium
por: Lee, Claudia, et al.
Publicado: (2020)

G Protein-Coupled Receptor Kinase 2 (GRK2) and 5 (GRK5) Exhibit Selective Phosphorylation of the Neurotensin Receptor in Vitro
por: Inagaki, Sayaka, et al.
Publicado: (2015)

SUN-665 Peripheral CB(1)R Blocker Improves Metabolism in Diet Induced Obese Mice Independent of Hepatic FGF21
por: Liu, Jie, et al.
Publicado: (2020)

Quantification of Beta Adrenergic Receptor Subtypes in Beta-Arrestin Knockout Mouse Airways
por: Hegde, Akhil, et al.
Publicado: (2015)

Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
por: Nakajima, Ken-ichiro, et al.
Publicado: (2016)

Corrigendum: Gs-coupled GPCR signalling in AgRP neurons triggers sustained increase in food intake
por: Nakajima, Ken-ichiro, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nj83kh25n7jkob2b0ptlkq53nl