Variation in Coronary Atherosclerosis Severity Related to a Distinct LDL (Low-Density Lipoprotein) Profile: Findings From a Familial Hypercholesterolemia Pig Model

In an adult porcine model of familial hypercholesterolemia (FH), coronary plaque development was characterized. To elucidate the underlying mechanisms of the observed inter-individual variation in disease severity, detailed lipoprotein profiles were determined. APPROACH AND RESULTS: FH pigs (3 years...

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Detalles Bibliográficos
Autores principales: Hoogendoorn, Ayla, den Hoedt, Sandra, Hartman, Eline M.J., Krabbendam-Peters, Ilona, te Lintel Hekkert, Maaike, van der Zee, Leonie, van Gaalen, Kim, Witberg, Karen Th., Dorst, Kristien, Ligthart, Jurgen M.R., Drouet, Ludovic, Van der Heiden, Kim, van Lennep, Jeanine Roeters, van der Steen, Antonius F.W., Duncker, Dirk J., Mulder, Monique T., Wentzel, Jolanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6818985/
https://www.ncbi.nlm.nih.gov/pubmed/31554418
http://dx.doi.org/10.1161/ATVBAHA.119.313246

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