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The release of tryptase from mast cells promote tumor cell metastasis via exosomes

BACKGROUND: Cancer cells release exosomes and can be taken up by mast cells (MCs), but the potential functional effects of MCs on tumor metastasis remain unknown. METHOD: Exosomes were isolated from the lung adenocarcinoma cell line A549, and the uptake of PKH26-labeled exosomes by bone marrow MCs w...

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Detalles Bibliográficos
Autores principales:	Xiao, Hui, He, Mudan, Xie, Guogang, Liu, Yanan, Zhao, Yuxia, Ye, Xiong, Li, Xingjing, Zhang, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819443/ https://www.ncbi.nlm.nih.gov/pubmed/31664930 http://dx.doi.org/10.1186/s12885-019-6203-2

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