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Attenuation of hedgehog/GLI signaling by NT1721 extends survival in pancreatic cancer
BACKGROUND: Pancreatic cancer is one of the most lethal malignancies due to frequent late diagnosis, aggressive tumor growth and metastasis formation. Continuously raising incidence rates of pancreatic cancer and a lack of significant improvement in survival rates over the past 30 years highlight th...
Autores principales: | Kowolik, Claudia M., Lin, Min, Xie, Jun, Overman, Larry E., Horne, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819529/ https://www.ncbi.nlm.nih.gov/pubmed/31661013 http://dx.doi.org/10.1186/s13046-019-1445-z |
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