Changing indications for enucleation and selected unusual pathologies

PURPOSE: To survey clinical indications for enucleations received within a single specialist ophthalmic pathology department over a 21-year period. METHODS: Cases were identified from the departmental records and categorised by indication type as well as by year. RESULTS: Over time, there has been a decreasing trend in eyes removed for end-stage indications such as phthisis, blindness or pain, as well as a decrease in eyes removed following trauma. CONCLUSION: With the reducing number of eyes removed for end-stage disease and trauma, the majority of enucleations performed are now for malignancy. However, eyes are still removed for other indications. A selection of rarer pathologies is presented.