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Hydroxyindole-O-methyltransferase (HIOMT) activity in the retina of melatonin-proficient mice

Numerous pieces of evidence support the expression by the mammalian retina of Hydroxyindole-O-methyltransferase (HIOMT, EC 2.1.1.4), the enzyme directly responsible for the biosynthesis of the pineal chronobiotic hormone melatonin (MLT). However, conflicting results obtained so far by enzyme-kinetic...

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Detalles Bibliográficos
Autores principales:	Betti, Laura, Palego, Lionella, Demontis, Gian Carlo, Miraglia, Fabiana, Giannaccini, Gino
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819757/ https://www.ncbi.nlm.nih.gov/pubmed/31687544 http://dx.doi.org/10.1016/j.heliyon.2019.e02417

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