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Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model

Hepatitis B virus (HBV) core protein (HBc) accumulates frequent mutations in natural infection. Wild-type HBV is known to secrete predominantly virions containing mature DNA genome. However, a frequent naturally occurring HBc variant, I97L, changing from an isoleucine to a leucine at amino acid 97,...

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Detalles Bibliográficos
Autores principales:	Wu, Szu-Yao, Chang, Ya-Shu, Chu, Tien-Hua, Shih, Chiaho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819939/ https://www.ncbi.nlm.nih.gov/pubmed/31462567 http://dx.doi.org/10.1128/JVI.01001-19

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