Association of Apolipoprotein E ɛ4, Educational Level, and Sex With Tau Deposition and Tau-Mediated Metabolic Dysfunction in Older Adults

IMPORTANCE: While amyloidosis is an early event in the Alzheimer disease (AD) biomarker cascade, a complex interplay among the apolipoprotein E (APOE) ɛ4 allele, educational levels, and sex may be associated with an individual’s resilience to dementia. OBJECTIVE: To assess whether APOE ɛ4, education...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramanan, Vijay K, Castillo, Anna M., Knopman, David S., Graff-Radford, Jonathan, Lowe, Val J., Petersen, Ronald C., Jack, Clifford R., Mielke, Michelle M., Vemuri, Prashanthi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820045/
https://www.ncbi.nlm.nih.gov/pubmed/31642932
http://dx.doi.org/10.1001/jamanetworkopen.2019.13909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820045/
https://www.ncbi.nlm.nih.gov/pubmed/31642932
http://dx.doi.org/10.1001/jamanetworkopen.2019.13909

Ejemplares similares