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Association of Apolipoprotein E ɛ4, Educational Level, and Sex With Tau Deposition and Tau-Mediated Metabolic Dysfunction in Older Adults

IMPORTANCE: While amyloidosis is an early event in the Alzheimer disease (AD) biomarker cascade, a complex interplay among the apolipoprotein E (APOE) ɛ4 allele, educational levels, and sex may be associated with an individual’s resilience to dementia. OBJECTIVE: To assess whether APOE ɛ4, education...

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Detalles Bibliográficos
Autores principales:	Ramanan, Vijay K, Castillo, Anna M., Knopman, David S., Graff-Radford, Jonathan, Lowe, Val J., Petersen, Ronald C., Jack, Clifford R., Mielke, Michelle M., Vemuri, Prashanthi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820045/ https://www.ncbi.nlm.nih.gov/pubmed/31642932 http://dx.doi.org/10.1001/jamanetworkopen.2019.13909

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