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Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

IMPORTANCE: Corticolimbic patterns of neurofibrillary tangle (NFT) accumulation define neuropathologic subtypes of Alzheimer disease (AD), which underlie the clinical heterogeneity observed antemortem. The cholinergic system, which is the target of acetylcholinesterase inhibitor therapy, is selectiv...

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Detalles Bibliográficos
Autores principales:	Hanna Al-Shaikh, Fadi S., Duara, Ranjan, Crook, Julia E., Lesser, Elizabeth R., Schaeverbeke, Jolien, Hinkle, Kelly M., Ross, Owen A., Ertekin-Taner, Nilufer, Pedraza, Otto, Dickson, Dennis W., Graff-Radford, Neill R., Murray, Melissa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820048/ https://www.ncbi.nlm.nih.gov/pubmed/31657834 http://dx.doi.org/10.1001/jamaneurol.2019.3606

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