Cargando…

Dynamic Emergence of Observed and Hidden Intra-tumor Heterogeneity

Intra-tumor heterogeneity is frequently observed in cancer patients, and it is associated with therapeutic resistance and disease relapse. However, its systematic assessment is still limited and often unfeasible. Here, we use a mathematical model of tumor progression to decipher how multiple clones...

Descripción completa

Detalles Bibliográficos
Autores principales: Raynaud, Franck, Mina, Marco, Ciriello, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820272/
https://www.ncbi.nlm.nih.gov/pubmed/31655256
http://dx.doi.org/10.1016/j.isci.2019.10.018